Cutting Edge NanoKnife Technology Now At Mercy

New Less Invasive Treatment Offers Hope for Patients with Pancreatic & Liver Cancers

October 16, 2020
Surgical Oncology at Mercy - Baltimore, MD

(Baltimore, MD) -- Mercy Medical Center is now among an exclusive group of hospitals to offer the state-of-the-art NanoKnife system which uses targeted electrical pulses to destroy cancerous tumor cells.

The NanoKnife system can be used to treat a variety of soft tissue tumors, but is typically employed as a late-stage therapy for locally advanced pancreatic and liver cancers.

According Debashish Bose, M.D., PhD, FACS of Surgical Oncology at Mercy, this next generation technology uses needles which are positioned around the tumor using ultrasound or CT scan guidance. Once the needles are properly positioned, electric current is passed between them, killing the cancer cells while avoiding damage to nearby healthy blood vessels, nerves and ducts.

“The NanoKnife provides an ablative approach to permanently damaging cancer cells that may be difficult to reach and treat with traditional methods. The carefully placed probes destroy the diseased tissue using pulsed, low-current, high-voltage electrical energy known as irreversible electroporation (IRE), while preserving structural elements in the tissue,” Dr. Bose explained.

“The electrical pulses create small holes in the membranes of the cancer cells, permanently damaging them, causing them to die off,” Dr. Bose said. 

Dr. Bose is an experienced liver and pancreatic surgeon, certified in Surgical Oncology, and board certified in General Surgery.  Dr. Bose and his colleagues at Mercy Medical Center treat benign and malignant disease of the abdominal cavity and peritoneal cavity, using both open and minimally invasive techniques such as laparoscopic and robotic surgery.  For such complex conditions, the team at Mercy applies a multidisciplinary approach to provide optimal care, which requires careful sequences of different types of treatment, including chemotherapy, radiation, surgery, Nanoknife, and other specialized therapies.



Dan Collins - Senior Director of Media Relations at Mercy Medical Center

Dan Collins, Senior Director of Media Relations

Email: dcollins@mdmercy.com Office: 410-332-9714 Cell: 410-375-7342

About Mercy

Founded in 1874 in downtown Baltimore by the Sisters of Mercy, Mercy Medical Center is a 183-licensed bed acute care university-affiliated teaching hospital. Mercy has been recognized as a top Maryland hospital by U.S. News & World Report; a Top 100 hospital for Women’s Health & Orthopedics by Healthgrades; is currently A-rated for Hospital Safety (Leapfrog Group), and is recognized by the American Nurses Credentialing Center as a Magnet Hospital. Mercy Medical Center is part of Mercy Health Services (MHS), the parent of Mercy’s primary care and specialty care physician enterprise, known as Mercy Personal Physicians, which employs more than 200 providers with locations in Baltimore, Lutherville, Overlea, Glen Burnie, Columbia and Reisterstown. For more information about Mercy, visit www.mdmercy.com, MDMercyMedia on FacebookTwitter, or call 1-800-MD-Mercy.

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