Since its inception, Mercy Medical Center has been blessed by the service and dedication of the Sisters of Mercy. Over the years, the Sisters have served in a wide range of roles in support of the hospital and its mission.

Topic of Study: Gastrointestinal Disease  This study is a phase 4 trial evaluating the effect of obeticholic acid on clinical outcomes in patients with primary biliary cholangitis. (302)

Topic of Study: Breast Cancer This global Phase 3, randomized, double blind study will evaluate the efficacy, safety, and pharmacokinetics of adjuvant Atezolizumab when given in combination with trastuzumab emtansine compared with placebo and trastuzumab emtansine for patients with residual invasive HER2-positive breast cancer following neoadjuvant taxane-based and HER2-targeted therapy including trastuzumab, who are at high risk of disease recurrence. (Clinicaltrials.gov ID#: NCT04873362)

Topic of Study: Gynecologic Cancer

The purpose of this phase II trial is to determine the toxicity and post-operative complications related to cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) as an initial treatment option for patients with ovarian, fallopian tube, or primary peritoneal cancers and its impact on quality of life. Subjects will be randomized to one of two treatment groups: CRS with HIPEC followed by combination chemotherapy, carboplatin and paclitaxel, or CRS only followed by combination chemotherapy carboplatin and paclitaxel.

Topic of Study: COVID-19 Infection Join a study to help us find ways to prevent and treat the long-term health effects of COVID, called Long COVID. Researchers will compare people who had COVID to people who have never had COVID - this helps us learn things that may be related to Long COVID, such as certain symptoms or health conditions. You can join if you've had COVID in the past 30 days. This study will not give anyone a treatment or medicine for COVID. If you join this study, you can still take treatments and medicines your doctor gives you.

Topic of Study: Appendiceal Cancer This is a study to define the pathological staging for appendiceal neoplasms by examining mutations of the genetic makeup of tumor tissue and to analyze prognostic factors associated with various stages of appendiceal cancer with peritoneal dissemination.

Topic of Study: Breast Cancer This study is designed to optimize endocrine therapy through motivational interviewing and text interventions. It will evaluate endocrine therapy adherence in women exposed to text message reminders only, telephone-based motivational interviewing counseling only, or both, versus usual care. (Clinicaltrials.gov ID#: NCT04379570)

Topic of Study: Breast Cancer

The purpose of this registry is to create a large-scale, population-based database. This database will match health information to genome information to look at the Agendia Breast Cancer suite and new gene associations. The Agendia Breast Cancer Suite includes MammaPrint® and BluePrint™, which are tests that help your doctor analyze and profile your breast cancer tumor. DiscoverPrint is for research purposes only. (Clinicaltrials.gov ID#: NCT03053193)

Topic of Study: Gynecologic Cancer The objective of this study is to collect patient specimens prospectively (tumor, blood, vaginal swab, and urine sample) from benign, high risk, and malignant surgeries in order to develop diagnostic biomarkers and targeted anticancer agents for gynecologic tumors. http://lifegenedna.com/