Learn more about a long-term health struggle and the trusting relationship one patient established with her doctor at The Institute for Digestive Health and Liver Disease.

Peggy has been a patient of Dr. Gregory Gasbarro's for some time, seeking treatment for the arthritis in her shoulder. After trying non-operative methods, it was time for surgery.

Topic of Study: Breast Cancer This global Phase 3, randomized, double blind study will evaluate the efficacy, safety, and pharmacokinetics of adjuvant Atezolizumab when given in combination with trastuzumab emtansine compared with placebo and trastuzumab emtansine for patients with residual invasive HER2-positive breast cancer following neoadjuvant taxane-based and HER2-targeted therapy including trastuzumab, who are at high risk of disease recurrence. (Clinicaltrials.gov ID#: NCT04873362)

Topic of Study: Gastrointestinal Disease  This study is a phase 4 trial evaluating the effect of obeticholic acid on clinical outcomes in patients with primary biliary cholangitis. (302)

Topic of Study: Gynecologic Cancer

The purpose of this phase II trial is to determine the toxicity and post-operative complications related to cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) as an initial treatment option for patients with ovarian, fallopian tube, or primary peritoneal cancers and its impact on quality of life. Subjects will be randomized to one of two treatment groups: CRS with HIPEC followed by combination chemotherapy, carboplatin and paclitaxel, or CRS only followed by combination chemotherapy carboplatin and paclitaxel.

Topic of Study: Breast Cancer This is a Phase III, randomized, open-label, multicenter study evaluating the efficacy and safety of Giredestrant plus Everolimus compared with the physician's choice of endocrine therapy plus Everolimus in patients with estrogen receptor-positive, HER2-negative, locally advanced or metastatic breast cancer. (Clinicaltrials.gov ID#: NCT05306340)

Topic of Study: Inflammatory Bowel Disease The goals of this study are to create a prospective cohort of well phenotyped adult IBD patients with serial clinical and patient reported data and biosamples collected throughout the course of their disease. This data will be used to identify predictors of response to IBD therapies and of disease relapse.

Topic of Study: COVID-19 Infection Join a study to help us find ways to prevent and treat the long-term health effects of COVID, called Long COVID. Researchers will compare people who had COVID to people who have never had COVID - this helps us learn things that may be related to Long COVID, such as certain symptoms or health conditions. You can join if you've had COVID in the past 30 days. This study will not give anyone a treatment or medicine for COVID. If you join this study, you can still take treatments and medicines your doctor gives you.

Topic of Study: Breast Cancer This is a Phase Ib/III, open-label, randomised study of Capivasertib plus CDK4/6 inhibitors and Fulvestrant versus CDK4/6 inhibitors and Fulvestrant in Hormone Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative locally advanced, unresectable or metastatic breast cancer. (Clinicaltrials.gov ID#: NCT04862663)