Topic of Study: Breast Cancer

The purpose of this registry is to create a large-scale, population-based database. This database will match health information to genome information to look at the Agendia Breast Cancer suite and new gene associations. The Agendia Breast Cancer Suite includes MammaPrint® and BluePrint™, which are tests that help your doctor analyze and profile your breast cancer tumor. DiscoverPrint is for research purposes only. (Clinicaltrials.gov ID#: NCT03053193)

Topic of Study: Inflammatory Bowel Disease This is a multicenter, prospective randomized controlled trial in which adults with IBD are randomized to four IBD self-help interventions to determine the impact of the interventions on patients' physical and psychosocial function and self-efficacy.

Topic of Study: Gynecologic Cancer The objective of this study is to collect patient specimens prospectively (tumor, blood, vaginal swab, and urine sample) from benign, high risk, and malignant surgeries in order to develop diagnostic biomarkers and targeted anticancer agents for gynecologic tumors. http://lifegenedna.com/

Topic of Study: Appendiceal Cancer The primary aim of the study is to determine the microbiological environment of the peritoneal tissues of patients undergoing cytoreductive surgery with intraoperative hyperthermic chemotherapy for appendix cancer with peritoneal spread.

Topic of Study: Breast Biopsy, Colorectal Cancer, Solid Tumors The Biorepository for Caris Life Sciences is designed for the purpose of making quality biospecimens and associated clinical data available for research studies related to advancing precision medicine and improving care for patients. (Clinicaltrials.gov ID#: NCT01499394)

Topic of Study: Breast Cancer This is a Phase 3 open-label, randomised study of Datopotamab Deruxtecan (Dato-DXd) with or without Durvalumab versus investigator’s choice of therapy in patients with Stage I-III Triple-negative breast cancer who have residual invasive disease in the breast and/or axillary lymph nodes at surgical resection following Neoadjuvant Systemic Therapy. (Clinicaltrials.gov ID#: NCT05629585)

Topic of Study: Inflammatory Bowel Disease This is a pragmatic, open-label, multicenter randomized controlled trial conducted in asymptomatic patients with IBD who have persistent moderate to severe endoscopic inflammation despite optimization of index targeted immunomodulatory (TIM). This clinical trial aims to collect and analyze data in patients with IBD who are currently receiving IBD medication(s) that targets their immune system (TIM) in routine clinical care, and to determine if switching to an alternative IBD medications will improve their disease outcome without increasing the burden of their treatment. (Clinicaltrials.gov ID# NCT05230173)